Zidovudine Induced Myopathy

Noguera Julian 07 Bibliografia - UB
Mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet 1991, 337: 508-510. Amaya R, Kozinetz C, McMeans A, Schwarzwald H, Kline M. Lipodystrophy syndrome in human immunodeficiency virus-infected children. ... Document Retrieval

Muscle-fiber Transdifferentiation In An Experimental Model Of ...
Muscle-fiber transdifferentiation in an experimental model of respiratory chain Results: Zidovudine induced a myopathy with mitochondrial DNA depletion, abnormalities in mitochondrial ultrastructure, and reduced cytochrome c oxidase activity. ... Access Full Source

Prolonged Period Before Pregnancy Has Not Been Evaluated.
Myopathy: Prolonged use of zidovudine has been associated with symptomatic myopathy [see Warnings and Precautions (5.2)]. Lactic Acidosis and Severe Hepatomegaly: Lactic acidosis and severe hepatomegaly with ... Return Doc

Zidovudine (AZT) induced Alterations In Mitochondrial ...
Zidovudine (AZT) induced alterations in mitochondrial biogenesis in rat striated muscles Damien Freyssenet, Martino DiCarlo, Patricia Escobar, Janice Grey, ... Read Here

RGH Pharmacy E-Bulletin - Auspharmacist.net.au
RGH Pharmacy E-Bulletin Volume 37 (1): February 8, 2010 The degree of zidovudine-induced myopathy is dependant on the duration and dose of therapy, with 17% of patients receiving long-term zidovudine experiencing some degree of myopathy. ... Doc Retrieval

Stavudine Induced Multiple Adverse Effects In HIV-Infected ...
Stavudine Induced Multiple Adverse Effects in HIV-Infected Patient Piyush Omprakash Somani, Amol Khot, Samit Jain, The major toxicities of NRTI therapy, particularly over the medium-term to long-term, include myopathy (zidovudine); neuropathy (stavudine, didanosine, zalcitabine); ... Fetch This Document

THE CHANGING FACE OF RHEUMATIC DISEASES IN HIV INFECTION
49 Muscle involvement 9.2 50 4.5 Fibromyalgia 1.0 Polymyositis/dermatomyositis 7.1 Zidovudine-induced myopathy 1.0 35 Sjögren-like syndrome/Diffuse infiltrative leukocytosis syndrome 11.2 10 3 THE CHANGING FACE OF RHEUMATIC DISEASES IN HIV INFECTION Author: vinay Last modified ... Fetch Document

Changes In Mitochondrial DNA As A Marker Of Nucleoside ...
MITOCHONDRIAL DNA LEVEL AS A MARKER OF NUCLEOSIDE TOXICITY Early studies on zidovudine-induced myopathy found a decrease in total mitochondrial DNA in mus-cle-biopsy specimens. 15-17 In vitro studies of various anti-HIV nucleoside analogues have also shown that ... Document Retrieval

Zidovudine Induces Downregulation Of Mitochondrial ...
Zidovudine Induces Downregulation of Mitochondrial drial myopathy, cardiomyopathy, and lipodystrophy associated with anti-HIV treatment using zidovudine (AZT) or 2=,3=-dide- in nucleoside analog-induced mitochondrial toxicity, and the ... Fetch Content

Reactions 504 - 4 Jun 1994 - Springer
Reactions 504 - 4 Jun 1994 Carnitine for zidovudine-induced myopathy? US investigators studied muscle biopsies in 21 patients with AIDS who had zidovudine-induced myopathy and ... Retrieve Content

Metabolic Abnormalities Skeletal Muscleof Patients Receiving ...
Zidovudine-induced Mitochondrial Myopathy 129. time constant for PCr recovery has been used to estimate the maximal rate of mitochondrial ATP synthesis, V,, (25, 37, 38). While the average time constant for PCr recovery was ... Retrieve Content

Nuclear And Mitochondrial Changes Of Muscle Fibers In AIDS ...
Zidovudine-induced myopathy. All of the light microscopic changes seen in the present patient's muscle biopsy have, among others, been previously reported in both, non-zidovudine- treated patients with AIDS [13, 23, 26, 30, 44, 45, 60, 69, 72], and zidovudine-treated ... Access Content

Cellular And Mitochondrial Toxicity Of zidovudine (AZT ...
Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine mitochondrial myopathy can be observed in patients treated with AZT, AZT, ddI and ddC induced cytoplasmic lipid droplet accumulations, increased lactate production and decreased activities of ... Return Document

Correspondence - Nejm.org
The detection of zidovudine-induced myopathy. 5 P ATRICK C HARIOT, M.D. N Chariot P, Drogou I, de Lacroix-Szmania I, et al. Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acido-sis, and mitochondrial DNA depletion. ... Retrieve Document

Survival Of A Human Immunodeficiency Patient With Nucleoside ...
2486 R. Chodock et al. bonate level, and is superior to baths containing other Schon EA. Depletion of muscle mitochondrial DNA in AIDS anions, such as acetate, in transfer of bicarbonate to patients with zidovudine-induced myopathy. ... View This Document

Rapid Communications Cardiac Mitochondrial DNA Polymerase-y ...
Athy.3 Dalakas et a14 reported a zidovudine-induced mitochondrial myopathy. Molecular studies revealed Lewis et al AZTInhibits Mitochondrial DNAPolymerase-y 345 dure was repeated twice. Thefinal pellet wasdistributed into 50-mLtubes, frozenin liquid N2, ... Retrieve Full Source

Mechanisms Of Zidovudine-Induced Mitochondrial Toxicity And ...
Mechanisms of Zidovudine-Induced Myopathy Several in vitro and in vivo studies have alluded to possible mechanisms leading to AZT-induced myopathy through the impairment of skeletal muscle mitochon-dria. Data suggest that the mechanism of mitochondrial ... Return Document

Zidovudine-induced Mitochondrial Disorder With Massive Liver ...
P. Chariot et al. Cunningham AL. Concurrent zidovudine-induced myopathy and hepatotoxicity in patients treated for HIV infection. ... Get Doc

Evere Lactic Acidosis Induced By Nucleoside Analogues In An ...
Nucleoside analogues can induce myopathy or hepatitis by means of mitochondrial mitochondriopathy induced by zidovudine and didanosine. [Roy P-M, Gouello J-P, Pennison-Besnier I, Chennebault J-M: Severe lactic acidosis induced by nucleoside analogues in an HIV-infected man. Ann Emerg ... Doc Viewer

Drug induced Muscle Disorders“ - - ResearchOnline@JCU
• Recognise risk factors for the different drug induced muscle disorders • Modify the risk for drug induced muscle disorders and manage symptoms if present Competencies Zidovudine myopathy resembles HIV-associated myopathy, with patients presenting with myalgia, fatigue and limb-girdle ... Access Full Source

Atrofia Muscolare - Wikipedia
L'atrofia muscolare è una riduzione della massa muscolare che ne determina una parziale o completa perdita di funzione. La principale conseguenza dell'atrofia è la debolezza muscolare , poiché la forza che può essere generata da un muscolo dipende (sebbene non esclusivamente) dalla sua massa. ... Read Article